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High-dose oral cyanocobalamin (1,000 mcg daily) is effective for many patients after sleeve gastrectomy, as a small proportion is absorbed passively without intrinsic factor

Vincristine caused a sharp increase in histone 3 phosphorylation at serine 10 (pS10-H3), likely due to its interference with mitotic spindle assembly, causing mitotic arrest ( Supplementary Figure S7A )